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Monday, July 28, 2014

Engineering Bacteria To Treat Chronic Disease

Researchers at Vanderbilt University have modified a bacteria to produce a therapeutic compound in the
guts of test mice. Studies have shown that beneficial bacteria naturally found in the gut plays a role in obesity, diabetes and cardiovascular disease, so the researchers set out to see if it was possible to manipulate gut microbiota to improve health.

When water containing the modified bacteria was added to the drinking water of mice fed a high-fat diet for eight weeks, the researchers found they ate less and had dramatically lower body fat, insulin resistance and fatty liver compared to mice that received control bacteria.

This has promise in treating diabetes, obesity and other chronic conditions.

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